beta 2 Microglobulin Rabbit Monoclonal Antibody
|
產品編號 |
產品名稱 |
產品包裝 |
產品價格 |
|
XY1633 |
beta 2 Microglobulin Rabbit Monoclonal Antibody |
50μl |
618.00元 |
|
來源 |
用途 |
交叉反應性 |
分子量 |
|
Rabbit |
WB, IP, IF, ICC |
H, M, R |
14.0kDa |
WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀釋液,可以用于Western檢測或其它適當用途時的一抗稀釋。
建議抗體使用時的稀釋比例如下(實際使用時需根據抗原水平的高低作適當調整):
|
WB |
IP |
IF |
IHC |
ICC |
FC |
ELISA |
ChIP |
|
1:1,000-1:2,000 |
1:10-1:50 |
1:50-1:200 |
- |
1:50-1:200 |
- |
- |
- |
抗體詳細信息如下:
|
About this Antibody |
|
|
Name |
beta 2 Microglobulin Rabbit Monoclonal Antibody |
|
Category |
Rabbit Monoclonal Antibody (RabMAb); Primary antibody |
|
Isotype |
IgG |
|
Purification |
XYfinity purification |
|
About the Immunogen |
|
|
Immunogen |
Recombinant protein |
|
Gene ID |
567(Human); 12010(Mouse); 24223(Rat) |
|
SwissProt |
P61769(Human); P01887(Mouse); P07151(Rat) |
|
Synonyms |
B2M; IMD43 |
|
Category |
Immunology/Inflamation |
|
Background |
Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an a heavy chain that contains three subdomains (α1, α2, α3), and a non-covalent associating light chain, known as β-2-Microglobulin. β-2-Microglobulin associates with the a3 subdomain of the a heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The α1 and α2 domains of the a heavy chain form the peptide antigen-binding cleft. Mice that lack β-2-Microglobulin protein show a normal distribution of T cells, yet have no mature CD4-8+ T cells and are defective in CD4-8+ T cell-mediated cytotoxicity. Interferon-γ can stimulate production of β-2-Microglobulin transcripts. The human β-2-Microglobulin gene maps to chromosome 15q21-q22.2 and encodes a 119 amino acid protein. Mutations in the β-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes. |
包裝清單:
|
產品編號 |
產品名稱 |
包裝 |
|
XY1633 |
beta 2 Microglobulin Rabbit Monoclonal Antibody |
50μl |
|
XY050 |
Western一抗稀釋液 |
50ml |
|
- |
說明書 |
1份 |
保存條件:
beta 2
Microglobulin Rabbit Monoclonal Antibody -20℃保存,Western一抗稀釋液-20℃或4℃保存,一年有效。Western一抗稀釋液優先推薦4℃保存,長期不使用可以考慮-20℃保存,但凍融可能會導致出現輕微的渾濁和少量不溶物。
注意事項:
如果本抗體用于Western blot (WB)、**熒光(IF)、**細胞化學(ICC)等實驗,請注意回收使用過的稀釋抗體。回收的抗體通常至少可以重復使用5-10次。稀釋后的抗體,包括已經使用過的稀釋抗體,請4℃保存。
回收后重復使用的抗體,使用方法同新鮮稀釋的抗體。如果在重復使用過程中發現抗體出現輕微混濁現象,可以10,000g離心1-3分鐘,取上清用于后續檢測。如果回收的抗體出現明顯的絮狀物或長霉長菌等情況,則可以考慮廢棄該抗體。
提供的Western一抗稀釋液也可以用于**熒光(IF)、**組化(IHC)、**細胞化學(ICC)等適當用途。如果希望獲得*佳的檢測效果,請考慮使用上述檢測專用的一抗稀釋液。
本產品**于專業人員的科學研究用,不得用于臨床診斷或**,不得用于食品或藥品,不得存放于普通住宅內。
為了您的**和健康,請穿實驗服并戴一次性手套操作。
- 溫馨提示:為規避購買風險,建議您在購買前務必確認供應商資質與產品質量。
- 免責申明:以上內容為注冊會員自行發布,若信息的真實性、合法性存在爭議,平臺將會監督協助處理,歡迎舉報


