Phospho-IRF3 (Ser386) Rabbit Monoclonal Antibody
|
產品編號
|
產品名稱
|
產品包裝
|
產品價格
|
|
XY1594
|
Phospho-IRF3
(Ser386) Rabbit Monoclonal Antibody
|
50μl
|
618.00元
|
|
來源
|
用途
|
交叉反應性
|
分子量
|
|
Rabbit
|
WB, IF, ICC
|
H
|
47.0kDa
|
WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀釋液，可以用于Western檢測或其它適當用途時的一抗稀釋。
建議抗體使用時的稀釋比例如下(實際使用時需根據抗原水平的高低作適當調整)：
|
WB
|
IP
|
IF
|
IHC
|
ICC
|
FC
|
ELISA
|
ChIP
|
|
1:1,000
|
-
|
1:50-1:200
|
-
|
1:50-1:200
|
-
|
-
|
-
|
抗體詳細信息如下:
|
About this
Antibody
|
|
Name
|
Phospho-IRF3
(Ser386) Rabbit Monoclonal Antibody
|
|
Category
|
Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
|
|
Isotype
|
IgG
|
|
Purification
|
XYfinity
purification
|
|
About the
Immunogen
|
|
Immunogen
|
Recombinant
protein
|
|
Gene ID
|
3661(Human)
|
|
SwissProt
|
Q14653(Human)
|
|
Synonyms
|
-
|
|
Category
|
Immunology/Inflamation
|
|
Background
|
Interferon
regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel
DNA-binding factors that function as regulators of both type I interferon
(interferon-α and β) and
interferon-inducible genes. The two factors are structurally related,
particularly in their N-terminal regions, which confer DNA binding
specificity. In addition, both bind to the same sequence within the promoters
of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon
transcription, while IRF-2 binds to the same cis elements and represses IRF-1
action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic
manner in regulating cell growth; overexpression of the repressor IRF-2 leads
to cell transformation while concomitant overexpression of IRF-1 causes
reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding
proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP).
|
包裝清單:
|
產品編號
|
產品名稱
|
包裝
|
|
XY1594
|
Phospho-IRF3
(Ser386) Rabbit Monoclonal Antibody
|
50μl
|
|
XY050
|
Western一抗稀釋液
|
50ml
|
|
-
|
說明書
|
1份
|
保存條件:
Phospho-IRF3
(Ser386) Rabbit Monoclonal Antibody -20℃保存，Western一抗稀釋液-20℃或4℃保存，一年有效。Western一抗稀釋液優先推薦4℃保存，長期不使用可以考慮-20℃保存，但凍融可能會導致出現輕微的渾濁和少量不溶物。
注意事項:
如果本抗體用于Western blot (WB)、**熒光(IF)、**細胞化學(ICC)等實驗，請注意回收使用過的稀釋抗體。回收的抗體通常至少可以重復使用5-10次。稀釋后的抗體，包括已經使用過的稀釋抗體，請4℃保存。
回收后重復使用的抗體，使用方法同新鮮稀釋的抗體。如果在重復使用過程中發現抗體出現輕微混濁現象，可以10,000g離心1-3分鐘，取上清用于后續檢測。如果回收的抗體出現明顯的絮狀物或長霉長菌等情況，則可以考慮廢棄該抗體。
提供的Western一抗稀釋液也可以用于**熒光(IF)、**組化(IHC)、**細胞化學(ICC)等適當用途。如果希望獲得*佳的檢測效果，請考慮使用上述檢測專用的一抗稀釋液。
本產品**于專業人員的科學研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內。
為了您的**和健康，請穿實驗服并戴一次性手套操作。
- 溫馨提示：為規避購買風險，建議您在購買前務必確認供應商資質與產品質量。
- 免責申明：以上內容為注冊會員自行發布，若信息的真實性、合法性存在爭議，平臺將會監督協助處理，歡迎舉報